Characteristics and Treatment of Patients with Breast Implant-Associated Anaplastic Large Cell Lymphoma Presenting with Aggressive Features.

INTRODUCTION: Breast implant-associated anaplastic large cell lymphoma (BI-ALCL) is a T-cell lymphoma arising around breast implants. Although initially considered as an “indolent” lymphoma, a subset of patients display more insidious disease marked by persistent and recurrent growth refractory to treatment. 1,2,3,4 The purpose of this study is to evaluate cases of BI-ALCL presenting with aggressive features: bilateral disease, lymph node involvement, and/or death of disease.